Translucence Biosystems is named a finalist in Octane's 2021 High Tech Awards (HTA)
We recently partnered with Zeiss Microscopy
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Fast and reliable 3D analysis of biological samples

This is more than just microscopy — this is a revolutionary system of cutting-edge tools and technologies for next-generation 3D histology.

We are enabling the dimensional shift from 2D to 3D tissue histology, developing tissue clearing methods, assays, imaging technology, machine learning-enabled data processing tools and novel methods for big data statistical analysis of spatial anatomy.

Increase access to the intricate 3D structure of the brain and other complex organs with powerful workflows

unique expertise in tissue clearing

light sheet imaging with our Mesoscale imaging System™

Pipeline for computational 3D reconstruction

Machine learning-based image analysis

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Imagine entire 3D cell cultures which preserve structural integrity by combining with tissue clearing methods

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Our services

Whole-brain assays

neuronal activity



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Custom services


tissue imaging

tissue quantification

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Latest research and news

June 3rd

Winning Video at BRAIN Initiative Investigators Meeting

We were so happy today to find out that we were the winners of the "Show us your Brains" video contest at this year’s BRAIN Initiative investigators meeting. Our video shows a Thy1-GFP mouse brain imaged in ~40 minutes with a 2.5x objective on a ZEISS Lightsheet Z.1 microscope equipped with our Mesoscale Imagine System.
Damian Wheeler
April 28th

Translucence is Studying the Effects of COVID-19 on the Brain

Translucence Biosystems has entered into a collaborative research project with the lab of Thomas Lane at UC Irvine to look at the effects of coronaviruses, including  SARS-CoV, on neuroinflammation. We are excited to apply our technology for whole-brain measurements of various aspects of neuroinflammation to help understand the mechanisms underlying the cognitive effects of COVID-19.
Damian Wheeler
March 24th

Translucence and Zeiss Team Up to Expand Possibilities for 3D Tissue Imaging

We are excited to announce that Translucence Biosystems has entered into a collaborative and strategic relationship with Carl Zeiss AG to promote the use of the Mesoscale Imaging SystemTM with the new ZEISS Lightsheet 7 microscope, designed to advance the 3D histology revolution.
Damian Wheeler

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Please, contact via us direct email info@translucencebio.comand