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The Translucence Neuronal Activity Tissue Clearing Kit provides a simple solution for simultaneous measurement of cFos and Npas4 throughout the brain, enabling cellular-resolution monitoring of recent neuronal activity-dependent signal transduction. The Translucence Neuronal Activity Tissue Clearing Kit is an ideal solution for next-generation 3D histology, making it the go-to option for researchers looking to streamline their processes.
Our Neuronal Activity Tissue Clearing Kit empowers you to capture activity patterns across the entire brain by measuring the expression of immediate-early genes (IEGs) Npas4 and cFos at single-cell resolution.
While cFos is widely used as a marker of neuronal activity, its expression is also associated with other signaling pathways, such as cAMP elevations, neurotrophins, and other paracrine factors, which reduces its specificity as a marker of pure neuronal activity. In contrast, Npas4 is precisely regulated by Ca2+-dependent signaling downstream of neuronal activity.
Compared to traditional methods, the Translucence Kit offers a more efficient, reliable, and streamlined approach. It eliminates the need for complicated and unreliable processes, providing researchers with the simplicity they need to achieve precise and accurate measurements.
Reagents and Disposables for 5 Whole Mouse Brains:
Please note that our eCommerce platform currently offers shipping exclusively within the United States. For all orders within the US, a flat shipping rate of $90 will apply.
For customers located outside the United States who are interested in purchasing our tissue clearing kit, our team is here to assist you in completing your order and providing information on international shipping options. We kindly request you to contact our dedicated kits team at kits@translucencebio.com.
Taxes info for buyers from USA
Please note that purchases placed outside the United States may be subject to additional duties or taxes, which will be the recipient's responsibility. For more in-depth information on our Neuronal Activity Tissue Clearing Kit, visit our product's informational page.
Our Translucence Tissue Clearing Kit offers a base kit option without Npas4 antibodies, allowing you to use your own antibodies.
Become an early-access user and help us shape the future of neuronal activity research. Early-access users will receive a 30% discount in return for sharing their valuable insights with our team. Inquire about our base kit via email kits@translucencebio.com or just fill in the form.
