We are enabling the dimensional shift from 2D to 3D tissue histology, developing tissue clearing methods, assays, imaging technology, machine learning-enabled data processing tools and novel methods for big data statistical analysis of spatial anatomy.
Experts in tissue clearing and staining methods
Light sheet imaging on ZEISS Lightsheet Z.1 and Lightsheet 7 microscopes using our Mesoscale imaging System™
Pipeline for computational 3D reconstruction
Machine learning-based image analysis
Use our validated antibodies to measure cFos and Npas4, providing rich, detailed insights into systems-level activity.
The Translucence Neuronal Activity Tissue Clearing Kit is an ideal solution for next-generation 3D histology, making it the go-to option for researchers looking to streamline their processes.
Discount for new users
The Universal Tissue Clearing Kit provides a robust solution for all your tissue clearing needs.
We developed the Mesoscale Imaging System, which makes the ZEISS Lightsheet Z.1 and Lightsheet 7 microscopes compatible with the high refractive index solutions used in iDISCO+ and other tissue clearing methods.
The system’s components exploit the superior optics of the ZEISS Lightsheet Z.1 and Lightsheet 7 microscopes and tune them for cleared tissue.
Translucence Biosystems participated in the Society for Neuroscience annual meeting, held November 15–19, 2025, in San Diego, California. The team hosted booth #3224, where they connected with the neuroscience community and discussed how tissue clearing can help accelerate neuroscience research. The team also presented five posters showcasing advancements in high-resolution whole-brain clearing, imaging, and analysis. Together, these posters highlighted tools and techniques that address the limitations of traditional histology, including tissue clearing, light sheet imaging, AI-powered 3D quantification, and cloud-based platforms that enable comprehensive whole-brain and organ-level insights at scale. See an outline of the posters presented below!
Translucence Biosystems recently participated in the Alzheimer's Association International Conference® (AAIC25), where CEO Damian Wheeler presented two posters demonstrating Translucence's whole-brain 3D tissue clearing techniques and AI-powered quantification pipeline. These presentations highlighted next-generation methodologies for quantifying disease burden and mapping therapeutic biodistribution at cellular resolution across the entire brain.
Translucence Biosystems recently hosted an engaging Brunch and Learn event in partnership with the UC San Diego School of Medicine Microscopy Core. The session welcomed faculty, researchers, and students for an introduction to tissue clearing methodologies, best practices, and examples of practical applications across various research domains, followed by a Q&A portion.
Send us your questions and we will get back to you as soon as possible.
info@translucencebio.com
